Lifeasible, a biotechnology company specializing in agricultural research, today announced an update to its yeast-based high-throughput screening platform, aimed at helping researchers rapidly identify plant genes that confer resistance to environmental stressors, pests, pathogens, and heavy metals.
Plants are increasingly facing challenges such as persistent heavy metal contamination in soil, disease attacks, and other environmental stresses. These factors significantly affect plant growth, yield, and crop quality. Therefore, identifying genes associated with resistance is crucial for modern breeding programs. Traditional screening methods are often slow, time-consuming, and have limited throughput, necessitating faster and more cost-effective approaches. In toxicology and stress response studies, model systems such as yeast provide a viable alternative to animal models, enabling high-throughput gene function analysis at a lower cost.
Backed by years of experience in molecular biology, Lifeasible now offers one-stop services for high-throughput resistance gene screening using yeast. Main services include: construction of yeast expression library; isolation of RNA and construction of cDNA library; high-throughput screening for resistance genes; preparation of yeast working solution; exploration for appropriate adverse conditions; screening of positive yeast clones under adverse conditions; gene identification of yeast positive clones; protein-induced expression and validation; phenotypic validation of yeast; knock-out yeast strain creation and transformation; and complement (overexpression) verification.
“We are excited about the update of our yeast-based high-throughput screening platform. By combining the speed and flexibility of yeast genetics with a robust screening workflow, we are sure scientists will explore complex resistance mechanisms more efficiently, thus unlocking new possibilities in plant biotechnology and crop improvement,” commented Isla, a representative from Lifeasible.
Over the years, Lifeasible has provided a wide range of services in plant biotechnology, including gene cloning, gene expression, modification, protein-protein or protein-DNA interactions, cell imaging, and phytochemical analysis to meet diversified research needs.
